The OneAir Lab detection system uses advanced sensing technology and modular sensor architecture to identify and monitor a wide range of health hazards. The OneAir Medical breath system focuses on personal health conditions including flu, RSV, and Covid-19; the OneAir Environment wall-mounted system focuses on interior environment hazards, including airborne particulates and mold. The system uses a novel array of nanoscale materials to detect distinct volatile organic compounds (VOCs) and machine learning to distinguish the presence of hazardous biomarkers. The system can be modified to respond to emerging health hazards, and sensors can easily be swapped out to accommodate evolving healthcare needs.